The FDA is said to have as of late instituted a crack down on weight loss supplements as a result of really serious side effects and even death related to some dietary supplements like ephedra. The ban on ephedra items resulted to the introduction of so-called ephedra free weight loss supplements, these too have been shown to yield their fair share of issues and they too may very well be meant to the same fate as ephedra.

These ephedra free drugs are said to trigger an increase in heart rate and a few other unwanted effects on healthy persons as outlined by a health expert who participated in the research project.

The examination conducted through the University of California at Berkeley was the primary one to look into the health effects of reformulated weight loss supplements. Some of the things investigated for included blood pressure and heart beat rate of volunteers who were given reformulated weight loss supplements created from extracts of bitter orange.

Since the ban slapped on ephedra by FDA, a growing figure of weight loss product manufactures have converted to extracts of bitter orange. The USB investigation involved 20 healthy volunteers, who were given sole doses of a weight loss supplement or a placebo.

The diet supplements screened in the study were Xenadrine EFX and Advantra Z, each of which includes bitter orange extracts. The managed drug was shown to effect a boost in cardiovascular pulse rate of up to 16 beats in one minute. The Thermogenic Xenadrine EFX in particular was shown to rev up heartbeat by 13 per cent, a thing that makes it almost similar in performance to ephedra.

Bitter orange extracts have synephrine, a part present in over 90% of citrus fruits but found in larger concentrations in fruits such as Sour orange, Zhi shi and bitter orange and which can be popularly used as a medicine in the control of respiratory tract congestion and high blood pressure. Xenadrine EFX includes a stimulant in the element, usually caffeine. The amount of caffeine is Xenadrine is estimated to be very similar to 3 coffee cups. This is the element responsible for the rise in blood pressure and people using this product are cautioned against over dosage.

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Since the ban slapped on ephedra by FDA, an increasing number of weight loss product manufactures have turned to extracts of bitter lemon. The USB study involved 20 healthy volunteers, who were given single doses of a weight loss supplement or a placebo.

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